The French Open champion was given a lesson in hard-court tennis by Blake, who equalled his best performance at a grand slam event.
The top seed can expect a tougher test against the fast-rising Indian.
A summary of Friday's action at the US Open.
A summary of Sunday's action at the US Open.
Images from Day 6 of the 2021 US Open in New York on Saturday.
Serena Williams was the runner-up in Flushing Meadows each of the past two years
IMAGES from Day 1 of the US Open played Flushing Meadows, New York, United States, on Monday.
Here are five things to watch for on day eight of the US Open on Monday.
Novak Djokovic took a first unsteady step toward completing the calendar-year Grand Slam on Tuesday as the Serb laboured into the second round of the US Open with a 6-1, 6-7(5), 6-2, 6-1 win over dashing Danish teenager Holger Rune.
The win burnished Murray's reputation as one of the world's leading doubles exponents,
Juan Sebastian Cabal and Robert Farah became the first Colombians to win the US Open men's doubles title.
Roberta Vinci beat her opponent and the rain to storm into the quarter-finals of the US Open on Monday just before a thunderstorm forced play to be suspended.
World number one Karolina Pliskova needed just 46 minutes to defeat American Jennifer Brady 6-1, 6-0 at Arthur Ashe Stadium and punch her ticket to the quarter-finals at the US Open on Monday.
'There is so much excitement brewing about Wednesday's Alcaraz and Rune quarter-finals showdown -- it could well be a juicy foretaste of things to come.'
IMAGES from Day 6 of the 2023 US Open on Saturday.
Australia must show a bit of "mongrel" and gel as a team if they are to lift the Ashes against England, former captain Steve Waugh has said.
American Rajeev Ram and Britain's Joe Salisbury beat Wesley Koolhof and Neal Skupski 7-6(4), 7-5 on Friday to become only the second pair to retain the US Open men's doubles title.
Mats Wilander said it was a 'miracle' that Nadal won two majors during the year.
The American great came into what is expected to be her final tournament as a 50-1 long-shot to win the title but after upsetting world number two Anett Kontaveit on Wednesday she is now 14-1
Novak Djokovic said he was "sad and empty" after a being disqualified from the US Open on Sunday after hitting a line judge in the throat with a ball during his fourth-round match against Spain's Pablo Carreno Busta.
A summary of Thursday's action at the US Open.
'But I'm sitting out for the people, for my Aussies, for the hundreds and thousands of Americans that have lost their lives, for all of you. It's my decision.'
Australia are shelving their controversial rotation policy for back-to-back Ashes campaigns that are in danger of falling into complete disarray barely two weeks prior to the opening test against England.
Images from Day 9 of the 2021 US Open in New York on Wednesday.
Venus Williams rejected the suggestion she might be content to serve as an inspiration to younger players after her 6-1, 0-6, 7-5 defeat to fellow American Sloane Stephens in the semi-finals.
Federer and world number one Nadal won the first three grand slam titles of the season as they came back to prominence with a bang, and nothing suggests their first-round opponents, American Frances Tiafoe and Serbian Dusan Lajovic, will bother them.
Sharapova was granted a wildcard entry to the last Grand Slam of the season but received a tough first-round draw in the shape of Romanian Halep.
A clash of generations will decide the US Open on Saturday with Serena Williams taking a fourth crack at Grand Slam history against teenager Bianca Andreescu, who was not even born when the American lifted her first Flushing Meadows trophy.
Barcelona's star footballer Lionel Messi was named the Best International Athlete award, while Serena Williams and Novak Djokovic, who recently won the Wimbledon singles titles, were named the best male and female tennis players respectively, at the 2015 ESPY Awards in California, on Wednesday night.
Images from Day 6 of the US Open in New York, on Saturday.
World number one Iga Swiatek beat Tunisia's Ons Jabeur 6-2, 7-6(5) in the US Open final on Saturday to claim her maiden trophy at Flushing Meadows and third Grand Slam title.
With poise beyond his 19 years and enviable stamina, Carlos Alcaraz faced down the crowd and Frances Tiafoe on Friday night to collect another thrilling win and reach the US Open final.
Frances Tiafoe is the first American man to make a US Open semi-final since Andy Roddick in 2006.
Venus Williams kept up with little sister Serena on Wednesday, beating 78th-ranked Timea Bacsinszky of Switzerland in straight sets to advance to the third round of the US Open.
Naomi Osaka said she had spent a lot of time during the coronavirus shutdown thinking about how she wanted to approach her tennis.
The 190th-ranked Indian stretched 20-time Grand Slam Champion Roger Federer to four sets in opening round of the US Open.
American Rajeev Ram and Briton Joe Salisbury overcame a slow start to beat Bruno Soares and Jamie Murray 3-6, 6-2, 6-2 in the US Open men's doubles final on Friday.
The victory secured a first Grand Slam doubles championship for Laura Siegemund and a third for Vera Zvonareva
Naomi Osaka now gets to test her mental strength against a revitalised Victoria Azarenka, who stunned Serena Williams in Thursday's other blockbuster semi-final.
